Software Engineering Leader

NATASHA
SINGH

I build the data and AI infrastructure that helps oncologists piece together medical timelines for children with brain tumors.

COMPLEXITY
WITH CARE.

A sick child's medical history is a puzzle scattered across clinics, labs, and specialists and sequencing centers. Finding better treatments or cures means bringing those puzzle pieces together

I build the systems that do that at scale. We integrate multi-modal data-genomics, imaging, clinical notes and architect the AI agents and workflows that can extract and interpret all brain tumor related variables.

But scale is nothing without trust. We design infrastructure that respects consent, enforces strict governance, and protects the most sensitive data in the world. Taking an ambiguous problem and shipping a platform that didn't exist yesterday is what I love to do.

Selected Projects

01 — 04

Current Focus

AI Patient
Chronicle

Leading 0-to-1 architecture for a clinical AI platform extracting temporal brain tumor variables from EHR, clinical notes, imaging, and genomics. Replacing fragmented manual workflows with a cohesive pipeline that produces structured timelines for multidisciplinary tumor board review. Collaboration across CHOP, Seattle Children's, and Children's Hospital of LA.

Agentic AIEHR Integration

Strategic Expansion

ARPA-H Pediatric
Care Expansion

Directing the architectural strategy for a $50M+ project building a centralized, multi-modal data hub. This ambitious undertaking unifies EHR, genomic, and imaging data, scaling real-time data acquisition infrastructure from 3 to 200 hospitals, fundamentally changing how pediatric care data is accessed for brain tumor patients.

AWS Step Functions, EMR, Lambda, S3, AthenaPython, PySpark, PostgreSQL

Infrastructure

Children's Brain
Tumor Network

The Children's Brain Tumor Network (CBTN) required a significant modernization of its genomic data transfer pipelines. I led the architectural overhaul that now executes secure petabyte-scale data transfer and validation across 35 institutions, eliminating operational bottlenecks and reducing production failures by nearly 100%.

AWS Step Functions, S3, Lambda, BatchPython, PostgresSQLTerraform, Github Actions

National Resource

NIH Kids First
Data Resource

Architected the authoritative clinical and genomic data layer for over 100K+ patients. By designing a standardized ingestion library and QC tooling layer, we reduced the time-to-ingest per research study from multiple days to 1 day, dramatically accelerating study onboarding velocity.

Python, Pandas, Docker, Github Actions

Experience & Education

Children's Hospital of Philadelphia

2017 — Present

Leading zero-to-one engineering initiatives for clinical AI and data platforms. Building teams that partner deeply with researchers and clinicians, fostering a culture of ownership where we never lose sight of the people at the end of the data pipeline.

Lockheed Martin

2009 — 2017

Spearheaded product lifecycle and technical vision for high-visibility applications, driving adoption and securing multi-million dollar R&D funding. Honed systems engineering rigor in zero-failure environments.

Education

Continuing Education

ByteByteGo AI Engineering Course
Maven Problem-First AI Engineering Course

Cornell University

Bsc Electrical & Computer Engineering
MEng Systems Engineering

Lockheed Martin

Engineering Leadership Development Program

CONTACT

Reach Out - Cheers :)

© 2026 Natasha Singh